STUDIES ON STREPTOCOCCAL BACTERIOPHAGES

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Studies on Streptococcal Bacteriophages

Evidence has been presented that the burst size in the Group A and Group C streptococcal phage-host systems are in general similar producing approximately 13 phage particles per infected coccus. The exception was the C1 phage which produced 10 times more virus particles than all the other phages tested. The eclipse period for the A25 phage-host system was found to extend for 34 min, while the C...

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Intergroup lysis and transduction by streptococcal bacteriophages.

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Studies on the Bacteriophages of Hemolytic Streptococci

The lysis of cell walls of hemolytic streptococci by a phage-associated lysin has been described. A method is presented for preparing the lysin from Group C streptococcal phage lysates. Following lysis almost all of the cell wall carbohydrate is recovered in solution. This material has the serological reactivity, physical-chemical properties, and values for nitrogen, rhamnose, and glucosamine s...

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Studies on Bacteriophages of Hemolytic Streptococci

The host ranges of bacteriophages for group A, types 1, 6, 12, and 25 and group C streptococci have been determined. The findings indicate that the susceptibility to these phages is primarily a group-specific phenomenon, although it is modified by several factors such as the hyaluronic acid capsule, lysogeny, and possibly the presence of surface proteins. Phage antibody studies indicate that wh...

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Studies on the Conjugation of Streptococcal Nucleoprotein*

Recent observations on conjugated proteins (l-6) raise the question as to whether the prevailing ideas concerning the nature of the attachment of nucleic acids with the proteins are valid. With certain exceptions it has generally been assumed that the nucleoproteins are salts of a polyvalent nucleic acid and a polyvalent base (protein) (7). The ideas that nucleoproteins are salt-like (polar), o...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1968

ISSN: 1540-9538,0022-1007

DOI: 10.1084/jem.127.3.475